How to Take SUNOSI
One pill. Once a day.
Take when you wake up in the morning
Take with or without food
Do not take within 9 hours of your bedtime
Starting treatment
with SUNOSI

SUNOSI comes in 75 mg and 150 mg tablets. If your doctor recommends starting with a 37.5 mg dose, you will need to split the 75 mg tablet in half. Always take SUNOSI exactly as prescribed.
After the first few days, your doctor may need to adjust your dose. Remember, everyone is different. If you are not seeing the results you want with SUNOSI, talk to your doctor about your dosing options. And, always speak up about any side effects.
Get a reminder texted to you when you need to refill your SUNOSI prescription.
How does SUNOSI work?
SUNOSI is thought to work on two areas in the brain that help keep you awake during the day.
Two natural chemicals in the brain—dopamine and norepinephrine—help you stay awake. SUNOSI is thought to improve wakefulness by increasing the activity of these natural chemicals.
SUNOSI is not a stimulant. It is known as a wake-promoting agent that is a medication called solriamfetol.

Do not take SUNOSI if you are taking, or have stopped taking within the past 14 days, a medicine used to treat depression called a monoamine oxidase inhibitor (MAOI).
Before taking SUNOSI, tell your doctor about all of your medical conditions, including if you:
- have heart problems, high blood pressure, kidney problems, diabetes, or high cholesterol.
- have had a heart attack or a stroke.
- have a history of mental health problems (including psychosis and bipolar disorders), or of drug or alcohol abuse or addiction.
- are pregnant or planning to become pregnant. It is not known if SUNOSI will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if SUNOSI passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take SUNOSI.
- SUNOSI does not treat the underlying cause of obstructive sleep apnea and does not take the place of any device prescribed for obstructive sleep apnea, such as a continuous positive airway pressure (CPAP) machine. It is important that you continue to use these treatments as prescribed by your healthcare provider.
Do not take SUNOSI if you are taking, or have stopped taking within the past 14 days, a medicine used to treat depression called a monoamine oxidase inhibitor (MAOI).
Before taking SUNOSI, tell your doctor about all of your medical conditions, including if you:- have heart problems, high blood pressure, kidney problems, diabetes, or high cholesterol.
- have had a heart attack or a stroke.
- have a history of mental health problems (including psychosis and bipolar disorders), or of drug or alcohol abuse or addiction.
- are pregnant or planning to become pregnant. It is not known if SUNOSI will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if SUNOSI passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take SUNOSI.
The most common side effects of SUNOSI include:
- •headache
- •nausea
- •decreased appetite
- •anxiety
- •problems sleeping
