What is SUNOSI?

SUNOSI is a once-daily prescription medicine used to improve wakefulness in adults with excessive daytime sleepiness, which is a real medical condition, due to obstructive sleep apnea (OSA) or narcolepsy.

What should I know about SUNOSI?

SUNOSI started working in as quickly as 1 hour in clinical studies at 12 weeks*.

SUNOSI does not treat the cause of obstructive sleep apnea or take the place of your CPAP.

SUNOSI is not a stimulant. It is a type of medication called a wake-promoting agent.

Do not take SUNOSI if you are taking, or have stopped taking within the past 14 days, a medicine used to treat depression called a monoamine oxidase inhibitor (MAOI).

SUNOSI was not shown to cause symptoms of withdrawal or dependence in clinical studies.

SUNOSI is a controlled substance because it can be a target for abuse. Keep SUNOSI in a safe place to protect it from theft.

It is not known if SUNOSI is safe and effective in children.

SUNOSI is made of a medication called solriamfetol.

*75 mg dose did not show improvement at one hour or across 9 hours in narcolepsy.

SUNOSI started working in as quickly as 1 hour in clinical studies at 12 weeks*.

SUNOSI does not treat the cause of obstructive sleep apnea or take the place of your CPAP.

SUNOSI is not a stimulant. It’s a type of medication called a wake-promoting agent.

Do not take SUNOSI if you are taking, or have stopped taking within the past 14 days, a medicine used to treat depression called a monoamine oxidase inhibitor (MAOI).

SUNOSI was not shown to cause symptoms of withdrawal or dependence in clinical studies.

SUNOSI is a controlled substance because it can be a target for abuse. Keep SUNOSI in a safe place to protect it from theft.

It is not known if SUNOSI is safe and effective in children.

SUNOSI is made of a medication called solriamfetol.

*75 mg dose did not show improvement at one hour or across 9 hours in narcolepsy.

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You could pay as little as $9 for a
full month of SUNOSI.

I was tired of being tired, so I talked to my doctor about SUNOSI. With treatment, I noticed a difference and started to feel more awake during the day.

— Patient with EDS due to OSA taking SUNOSI

Individual results may vary.

Important Safety Information

Do not take SUNOSI if you are taking, or have stopped taking within the past 14 days, a medicine used to treat depression called a monoamine oxidase inhibitor (MAOI).

Before taking SUNOSI, tell your doctor about all of your medical conditions, including if you:

have heart problems, high blood pressure, kidney problems, diabetes, or high cholesterol.
have had a heart attack or a stroke.
have a history of mental health problems (including psychosis and bipolar disorders), or of drug or alcohol abuse or addiction.
are pregnant or planning to become pregnant. It is not known if SUNOSI will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if SUNOSI passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take SUNOSI.

WHAT IS SUNOSI?

SUNOSI® (solriamfetol) is a prescription medicine used to improve wakefulness in adults with excessive daytime sleepiness due to narcolepsy or obstructive sleep apnea (OSA).

SUNOSI does not treat the underlying cause of obstructive sleep apnea and does not take the place of any device prescribed for obstructive sleep apnea, such as a continuous positive airway pressure (CPAP) machine. It is important that you continue to use these treatments as prescribed by your healthcare provider.

IMPORTANT SAFETY INFORMATION

Do not take SUNOSI if you are taking, or have stopped taking within the past 14 days, a medicine used to treat depression called a monoamine oxidase inhibitor (MAOI).

Before taking SUNOSI, tell your doctor about all of your medical conditions, including if you:

have heart problems, high blood pressure, kidney problems, diabetes, or high cholesterol.
have had a heart attack or a stroke.
have a history of mental health problems (including psychosis and bipolar disorders), or of drug or alcohol abuse or addiction.
are pregnant or planning to become pregnant. It is not known if SUNOSI will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if SUNOSI passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take SUNOSI.

What are the possible side effects of SUNOSI?

SUNOSI may cause serious side effects, including:

Increased blood pressure and heart rate. SUNOSI can cause blood pressure and heart rate increases that can increase the risk of heart attack, stroke, heart failure, and death. Your doctor should check your blood pressure before, and during, treatment with SUNOSI. Your doctor may decrease your dose or tell you to stop taking SUNOSI if you develop high blood pressure that does not go away during treatment with SUNOSI.

Mental (psychiatric) symptoms including anxiety, problems sleeping (insomnia), irritability, and agitation. Tell your doctor if you develop any of these symptoms. Your doctor may change your dose or tell you to stop taking SUNOSI if you develop side effects during treatment with SUNOSI.

The most common side effects of SUNOSI include:

•headache
•nausea

•decreased appetite
•anxiety

•problems sleeping

These are not all the possible side effects of SUNOSI. Call your doctor for advice about side effects.

SUNOSI is available in 75 mg and 150 mg tablets and is a federally controlled substance (CIV) because it contains solriamfetol that can be a target for people who abuse prescription medicines or street drugs. Keep SUNOSI in a safe place to protect it from theft. Never give or sell your SUNOSI to anyone else because it may cause death or harm them and it is against the law. Tell your doctor if you have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch

or call 1-800-FDA-1088.

Please see full Prescribing Information and Medication Guide.

Important Safety Information

Do not take SUNOSI if you are taking, or have stopped taking within the past 14 days, a medicine used to treat depression called a monoamine oxidase inhibitor (MAOI).

Before taking SUNOSI, tell your doctor about all of your medical conditions, including if you:

have heart problems, high blood pressure, kidney problems, diabetes, or high cholesterol.
have had a heart attack or a stroke.
have a history of mental health problems (including psychosis and bipolar disorders), or of drug or alcohol abuse or addiction.
are pregnant or planning to become pregnant. It is not known if SUNOSI will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if SUNOSI passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take SUNOSI.

WHAT IS SUNOSI?

SUNOSI® (solriamfetol) is a prescription medicine used to improve wakefulness in adults with excessive daytime sleepiness due to narcolepsy or obstructive sleep apnea (OSA).

SUNOSI does not treat the underlying cause of obstructive sleep apnea and does not take the place of any device prescribed for obstructive sleep apnea, such as a continuous positive airway pressure (CPAP) machine. It is important that you continue to use these treatments as prescribed by your healthcare provider.

IMPORTANT SAFETY INFORMATION

Do not take SUNOSI if you are taking, or have stopped taking within the past 14 days, a medicine used to treat depression called a monoamine oxidase inhibitor (MAOI).

Before taking SUNOSI, tell your doctor about all of your medical conditions, including if you:

have heart problems, high blood pressure, kidney problems, diabetes, or high cholesterol.
have had a heart attack or a stroke.
have a history of mental health problems (including psychosis and bipolar disorders), or of drug or alcohol abuse or addiction.
are pregnant or planning to become pregnant. It is not known if SUNOSI will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if SUNOSI passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take SUNOSI.

What are the possible side effects of SUNOSI?

SUNOSI may cause serious side effects, including:

The most common side effects of SUNOSI include:

•headache
•nausea

•decreased appetite
•anxiety

•problems sleeping

These are not all the possible side effects of SUNOSI. Call your doctor for advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch

or call 1-800-FDA-1088.

Please see full Prescribing Information and Medication Guide.

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