Frequently Asked
Questions about SUNOSI

SUNOSI is a once-daily prescription medicine used to improve wakefulness in adults with excessive daytime sleepiness due to narcolepsy or obstructive sleep apnea (OSA). Learn more about SUNOSI.
- SUNOSI does not treat the underlying cause of obstructive sleep apnea and does not take the place of any device prescribed for obstructive sleep apnea, such as a continuous positive airway pressure (CPAP) machine. It is important that you continue to use these treatments as prescribed by your healthcare provider.
- It is not known if SUNOSI is safe and effective in children.
SUNOSI improved wakefulness for up to 9 hours when measured at 12 weeks in two clinical studies. The 75 mg dose did not show improvement across 9 hours for people with narcolepsy.
SUNOSI started working within one hour when measured at 12 weeks in two
clinical studies. It is
important to talk to your healthcare provider about how quickly SUNOSI can
work for you. The 75 mg
dose did not show improvement at one hour for people with narcolepsy.
Learn more about
the study results.
SUNOSI is thought to act on two areas in the brain that help keep you awake during the day.
- Take SUNOSI exactly as your healthcare provider tells you to. Do not change your dose of SUNOSI without talking to your healthcare provider.
- Your healthcare provider may need to change the dose of SUNOSI to find the right dose for you. This is normal and may be a part of the process.
- Take SUNOSI by mouth 1 time each day when you first wake up. Avoid taking SUNOSI within 9 hours of your planned bedtime. If you take SUNOSI too close to your bedtime, you may find it harder to go to sleep.
- SUNOSI can be taken with or without food.
- Depending on your prescribed dose, your healthcare provider may tell you to swallow your SUNOSI tablet whole or split the SUNOSI tablet in half at the score line in the middle of the tablet. Ask your healthcare provider if you have questions about how to split the SUNOSI tablet in half the right way.
- If you take too much SUNOSI, call your healthcare provider or go to the nearest hospital emergency room right away.
The most common side effects experienced with SUNOSI include headache,
nausea, decreased appetite,
anxiety, and insomnia. These are not all the possible side effects of
SUNOSI. Call your healthcare
provider for medical advice about side effects. You may report side effects
to the FDA at 1-800-FDA-1088
or visit www.fda.gov/medwatch
Only you and your healthcare provider can decide if SUNOSI is right for you. If you’ve been diagnosed with obstructive sleep apnea or narcolepsy and often feel extremely tired during the day, talk with your healthcare provider and take the Daytime Sleepiness Quiz now.
Talk to your healthcare provider if you are pregnant or plan on becoming
pregnant, as you can work
together to decide if taking SUNOSI is right for you. There is a pregnancy
registry for women who
take SUNOSI during pregnancy that seeks to collect information about the
health of you and your
baby. Talk to your healthcare provider about how you can take part in this
registry. For more
information or to participate in the registry, call 1-877-283-6220
or go to www.SunosiPregnancyRegistry.com.
There are many types of healthcare providers who can help determine if SUNOSI is right for you. You can speak with your primary care physician or one of the following specialists: sleep specialist, pulmonologist, neurologist, or psychiatrist.
SUNOSI is available at most major retail pharmacies. If you have a valid prescription from your doctor and your pharmacy doesn’t have SUNOSI in stock, ask the pharmacist if they can order it for you.
Based on your eligibility, you may be able to pay as little as $9 for a one-month supply of SUNOSI. Click here to get a SUNOSI Savings Card. The cost of SUNOSI will vary depending on whether or not you have insurance, and if so, what type of insurance.
Axsome Therapeutics provides a variety of patient support services for SUNOSI. If you have questions or need assistance paying for your medication, SUNOSI On My Side may be able to help. You can call SUNOSI On My Side Monday-Friday, 8 AM-8 PM ET, at 1-800-805-8621 for more information about paying for your prescription.
Axsome Therapeutics provides a variety of patient support services for SUNOSI. If you have questions or need assistance paying for your medication, SUNOSI On My Side may be able to help. You can call SUNOSI On My Side Monday-Friday, 8 AM-8 PM ET, at 1-800-805-8621 for more information about paying for your prescription.
Are you taking SUNOSI for excessive daytime sleepiness due to obstructive
sleep
apnea or narcolepsy? We’d
love to hear your success story. Send us an email at SunosiShareMyStory@axsome.com.
Yes! Go to the SUNOSI Resources page to learn more and download the SUNOSI brochure.
Do not take SUNOSI if you are taking, or have stopped taking within the past 14 days, a medicine used to treat depression called a monoamine oxidase inhibitor (MAOI).
Before taking SUNOSI, tell your doctor about all of your medical conditions, including if you:
- have heart problems, high blood pressure, kidney problems, diabetes, or high cholesterol.
- have had a heart attack or a stroke.
- have a history of mental health problems (including psychosis and bipolar disorders), or of drug or alcohol abuse or addiction.
- are pregnant or planning to become pregnant. It is not known if SUNOSI will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if SUNOSI passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take SUNOSI.
- SUNOSI does not treat the underlying cause of OSA and SUNOSI does not take the place of any device prescribed for OSA, such as a continuous positive airway pressure (CPAP) machine. It is important that you continue to use these treatments as prescribed by your healthcare provider.
Do not take SUNOSI if you are taking, or have stopped taking within the past 14 days, a medicine used to treat depression called a monoamine oxidase inhibitor (MAOI).
Before taking SUNOSI, tell your doctor about all of your medical conditions, including if you:- have heart problems, high blood pressure, kidney problems, diabetes, or high cholesterol.
- have had a heart attack or a stroke.
- have a history of mental health problems (including psychosis and bipolar disorders), or of drug or alcohol abuse or addiction.
- are pregnant or planning to become pregnant. It is not known if SUNOSI will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if SUNOSI passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take SUNOSI.
The most common side effects of SUNOSI include:
- •headache
- •nausea
- •decreased appetite
- •anxiety
- •problems sleeping

SUN CON ISI 05/2022